Table 3.

AMR genes of L16 annotated in PATRIC.

AMR mechanism	Genes
Antibiotic activation enzyme	KatG
Antibiotic inactivation enzyme	AAC(3)-II,III,IV,VI,VIII,IX,X, BlaEC family, CatB family, CTX-M family, OXA-1 family
Antibiotic resistance gene cluster, cassette, or operon	MarA, MarB, MarR
Antibiotic target in susceptible species	Alr, Ddl, dxr, EF-G, EF-Tu, folA, Dfr, folP, gyrA, gyrB, inhA, fabI, Iso-tRNA, kasA, MurA, rho, rpoB, rpoC, S10p, S12p
Antibiotic target protection protein	BcrC
Efflux pump conferring antibiotic resistance	AcrAB-TolC, AcrAD-TolC, AcrEF-TolC, AcrZ, EmrAB-TolC, EmrD, EmrE, EmrKY-TolC, MacA, MacB, MdfA/Cmr, MdtABC-TolC, MdtEF-TolC, MdtL, MdtM, SugE, TolC/OpmH
Gene conferring resistance via absence	gidB
Protein altering cell wall charge conferring antibiotic resistance	GdpD, PgsA
Regulator modulating expression of antibiotic resistance genes	AcrAB-TolC, EmrAB-TolC, GadE, H-NS, OxyR