Table 3.
The comparison of alpha-shape descriptors and FD obtained from manual annotation and automatic segmentation.
| Parameter | Healthy (n = 15, DSC = 0.81870 ± 0.02360) | DR (n = 15, DSC = 0.58530 ± 0.0003) | DR vs Healthy (p-value*) | |||||
|---|---|---|---|---|---|---|---|---|
| Manual | Automatic | MRE (max, p-value+) | Manual | Automatic | MRE (max, p-value+) | M | A | |
| Opαmin, mean ± SD | 41.1 ± 5.6 | 52.4 ± 8.5 | 29% (80%, 0.476) | 44.0 ± 9.4 | 58.0 ± 17.1 | 37% (100%, 0.235) | 0.595 | 0.648 |
| OpA, mean ± SD | 1,063,768 ± 127,691 | 1,034, 863 ± 110,756 | 10% (24%, 0.144) | 1,046,821 ± 88,366 | 1,004,089 ± 118,917 | 10% (26%, 0.281) | 0.367 | 0.539 |
| VS, mean ± SD | 16,062 ± 3182 | 20,021 ± 2464 | 22% (39%, 0.087) | 24,516 ± 4270 | 18,113 ± 3,379 | 26% (49%, 0.008) | 0.305 | 0.202 |
| Gradα, mean ± SD | 366 ± 54 | 250 ± 57 | 31% (55%, 0.005) | 362 ± 89 | 213 ± 62 | 43% (66%, 0.064) | 0.967 | 0.249 |
| FD, mean ± SD | 1.47 ± 0.01 | 1.46 ± 0.01 | 0.9% (2%, 0.002) | 1.47 ± 0.01 |
1.45 ± 0.01 |
1.4% (3%, 0.004) | 0.01 | 0.01 |
DSC dice similarity coefficient with manual annotation as reference, MRE mean of the relative error with manual annotation as reference, Max maximum relative error with manual annotation as reference. n, number of images.
+Pearson correlation test with null hypothesis that the correlation coefficient is zero.
*Wilcoxon rank sum with null hypothesis that medians are equal between groups.