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. 2021 May 3;18(6):909–922. doi: 10.1111/iwj.13596

TABLE 4.

Summary of skin changes on both heels and sacrum immediately after loading and/or dressing removal

Intervention at heels
Loading Yes No Yes
Dressing No Yes Yes
Skin surface temperature
SCH ↑↑
Epidermal hydration ↑↑ ↑↑
TEWL
Erythema index ↑↑
Clinical signs of erythema ↑↑ ↑↑
Structural stiffness (Uf) ↑ (?) ↑↑
Biological elasticity (Ua/Uf) ↑ (?) ↑ (?)
Roughness (Rz) ↓↓ ↓↓
Stratum corneum thickness
Epidermal thickness
IL‐1 alpha ↑↑
Self‐reported pain One subject None None
Intervention at the sacrum
Skin surface temperature
SCH
Epidermal hydration ↑↑
TEWL
Erythema index
Clinical signs of erythema ↑↑ L
Structural stiffness (Uf)
Biological elasticity (Ua/Uf)
Roughness (Rz)
Epidermal thickness ↑ (?)
IL‐1 alpha
Self‐reported pain One subject None None

Abbreviations: SCH, stratum corneum hydration; TEWL, transepidermal water loss.