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. 2021 Nov 25;188(12):430. doi: 10.1007/s00604-021-05076-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Conjugation of GQDs with reverse transcriptase (RT) inhibitor CHI499 and targeting the HIV-1 RT. Upon treatment, the unstable imide bond between GQD and CHI499 is cleaved and GQDs interferes with the cell-virus interaction, while free CHI499 inhibits viral RT. Reprinted with permission from [97], Page No.3084, Copyright 2018 American Chemical Society