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The difference between aptamers and antibodies
| Aptamers | Antibodies | |
|---|---|---|
| Size | small (~ 12–30 kDa) | relatively big (~ 150 – 170 kDa) |
| Target | wide range | immune related protein |
| Synthesis | simple (chemically synthesis) | complicate (in vivo production) |
| Stability | stable | susceptible to temperature and pH |
| Modification | various modification | limited modification |
| Storage term | long | relatively short |
| Cost | low | high |
| Immunogenicity | low | high |
