Table II.
Inactivation of SARS-CoV-1 by hand sanitizers containing BAK or alcohol in EN14476 protocol testing [Test 2]
| Test 2a | Active Ingredient Concentration | Test Dayc | Initial inoculum [Log10TCID50d] | Virus recovery/[30 second] [Log10TCID50] | Virus Log Reductione [Log10TCID50] | Average Log10 Reductione |
|---|---|---|---|---|---|---|
| Hand Sanitizer Product B b | 0.089% Benzalkonium Chloride | 1 | 6.00 | ≤1.50 | ≥4.50 | ≥4.67 |
| 2 | 6.50 | ≤1.50 | ≥5.00 | |||
| 3 | 6.00 | ≤1.50 | ≥4.50 | |||
| Hand Sanitizer Product C | 80% Ethyl Alcohol | 1 | 6.00 | ≤1.50 | ≥4.50 | ≥4.67 |
| 2 | 6.50 | ≤1.50 | ≥5.00 | |||
| 3 | 6.00 | ≤1.50 | ≥4.50 |
a
Test 2 executed under GLP by Analytical Lab Group, MN.
b
Diluted 10:1 from concentrate 0.89% BAK to = 0.089% active BAK in test.
c
The test was run in full, on three separate test days.
d
TCID50 – Median Tissue Culture Infectious Dose.
e
> Inactivation beyond the limit of detection.