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Effect of AP39 on high-fat diet (HFD)-induced oxidative stress. (A) DHE staining (×400) was used for ROS detection in liver. (B–D) Levels of markers of oxidative stress, MDA, GSH and SOD, were measured with commercial kits. ROS, reactive oxygen species; MDA, malondialdehyde; GSH, glutathione; SOD, superoxide dismutase. **P<0.01 vs. Control; ^P<0.05, ^^P<0.01 vs. HFD.
