Skip to main content
. 2021 Nov 25;21:1273. doi: 10.1186/s12913-021-07300-8

Table 4.

Composition of each inappropriate category

overdosing improper administration frequency improper administration routes contraindication improper diluent volume medication not allowed for pediatric patients improper drug combination repeated administration indication-related off-label drug use total
year
2019 75.68% 63.97% 46.36% 97.22% 91.67% 74.54% 62.90% 64.60% 67.10% 67.62%
2020 24.32% 36.03% 53.64% 2.78% 8.33% 25.46% 37.10% 35.40% 32.90% 32.38%
Age groups, years
< 2 9.97% 18.14% 15.13% 0.00% 10.42% 3.55% 0.00% 2.65% 15.31% 14.98%
2–5 57.72% 33.52% 38.12% 0.00% 46.53% 8.20% 1.61% 12.68% 31.96% 34.85%
6–11 26.91% 22.48% 24.90% 25.00% 35.94% 22.77% 32.26% 32.15% 20.96% 22.12%
12–17 5.39% 25.86% 21.84% 75.00% 7.12% 65.48% 66.13% 52.51% 31.77% 28.06%
categories by the ATC drug classification
AIA 0.23% 1.21% 5.94% 0.00% 0.00% 6.24% 72.58% 4.42% 0.81% 0.98%
ATM 0.22% 1.98% 2.11% 63.89% 0.17% 10.65% 1.61% 0.00% 12.24% 8.86%
BLD 0.06% 0.88% 8.62% 0.00% 1.04% 0.00% 8.06% 1.77% 6.05% 4.36%
CVS 0.47% 3.58% 0.38% 0.00% 0.00% 0.37% 4.84% 1.47% 3.98% 3.41%
DRM 0.00% 0.57% 0.57% 22.22% 0.00% 0.00% 0.00% 0.29% 7.00% 4.87%
GEN 0.05% 0.08% 0.77% 0.00% 0.00% 16.40% 0.00% 0.00% 0.17% 0.33%
HRM 1.32% 0.13% 11.69% 0.00% 0.00% 0.00% 0.00% 8.55% 0.86% 0.88%
INF 5.35% 8.96% 9.77% 0.00% 92.53% 20.69% 11.29% 0.59% 16.34% 14.33%
MSK 0.09% 0.24% 0.00% 5.56% 0.00% 18.97% 0.00% 2.06% 0.85% 0.85%
NRV 5.03% 15.95% 0.19% 0.00% 0.00% 24.97% 0.00% 5.60% 6.13% 7.87%
RES 78.36% 34.45% 49.04% 0.00% 0.35% 0.12% 1.61% 74.93% 36.29% 40.15%
SNS 0.00% 0.68% 9.20% 8.33% 0.00% 0.00% 0.00% 0.29% 2.81% 2.10%
TCM 8.77% 31.24% 0.96% 0.00% 5.90% 0.49% 0.00% 0.00% 5.92% 10.61%
Others 0.04% 0.05% 0.77% 0.00% 0.00% 1.10% 0.00% 0.00% 0.54% 0.40%