TABLE 1.
Growth or inhibition of filamentous fungi in amphotericin B and itraconazole after 48 ha
Organism (no.) | Amphotericin B
|
Itraconazole
|
||
---|---|---|---|---|
0.5 μg/ml | 2.0 μg/ml | 0.25 μg/ml | 1.0 μg/ml | |
Aspergillus fumigatus (8) | 0 | 0 | 0 | 0 |
Aspergillus fumigatus (3) | + | 0 | 0 | 0 |
Aspergillus flavus (1) | 0 | 0 | 0 | 0 |
Aspergillus niger (5) | 0 | 0 | 0 | 0 |
Fusarium sp. (1) | + | + | + | + |
H. capsulatum (1) | 0 | 0 | 0 | 0 |
Mucor sp. (1) | 0 | 0 | + | + |
Paecilomyces sp. (1) | 0 | 0 | 0 | 0 |
Penicillium spp. (2) | 0 | 0 | 0 | 0 |
Penicillium sp. (1) | + | 0 | 0 | 0 |
Trichophyton sp. (1) | 0 | 0 | 0 | 0 |
C. parapsilosis ATCC 90018 (control) (1) | 0 | 0 | 0 | 0 |
Except for H. capsulatum (5 days) and Trichophyton (3 days). All strains except C. parapsilosis were resistant to fluconazole at 40 μg/ml. +, growth; 0, inhibition.