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. 2021 Nov 25;2021(11):CD009985. doi: 10.1002/14651858.CD009985.pub2

Quach 2015.

Study characteristics
Methods RCT.
RCT ‐ individual to determine the impact of an early medication reconciliation (MR) in patients evaluated in the emergency department (ED) and identify barriers to reconciling medication in the ED.
Unit of allocation: patients
Unit of analysis: patients
Participants Patients ≥ 65 years old, taking a high alert medication (i.e. anticoagulants, opioids, insulin), or if the patient’s physician deemed it necessary, from the University of California Davis Medical Center (UCDMC) in Sacramento (N = 307).
Elderly IP (ED)
Interventions Intervention Human resources, medication reconciliation
Patients agreeing to receive MR were randomly assigned to receive either:
Intervention: MR completed prior to admission
Control: MR standard of care
Outcomes Discrepancies in prescriptions
Notes No financial support stated
No trial number
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information provided
Allocation concealment (selection bias) Unclear risk No information provided
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk No information provided
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk All unintentional discrepancies were regarded as errors and were then given to a panel of experts for severity ranking (1 = severe error, 4 = non‐significant error). No information provided on the main outcome assessment (unintentional discrepancy)
Incomplete outcome data (attrition bias)
All outcomes Unclear risk No information provided.
Selective reporting (reporting bias) Unclear risk Insufficient information to permit judgement of ‘Low risk’ or ‘High risk’.
Conflict of interest Unclear risk No description
Other bias Unclear risk No information on baseline characteristics of included patients was provided. "A total of 307 patients were enrolled in the study (treatment = 134 and control = 173". The authors mentioned "barriers to MR included: constant movement of patients on the floor, frequent room changes, patients unable to give history due to acuity, inability to reach family or caregiver, and patients discharge before MR can be completed".