Effect of rutin and rutin glycoside on the production of nitric oxide (NO), Prostaglandin E (PGE) 2, tumor necrosis factor (TNF)-α and interleukin (IL)-6. RAW 264.7 cells were cultured with different rutin and rutin glycoside concentrations for 24 h with LPS (1 μg/mL). CTR−, Negative control. CTR+, Positive control (LPS). Results were represented as mean ± SD (n = 3). (A) Effect on NO; (B) Effect on PGE2; (C) Effect on TNF-α; (D) Effect on IL-6. Different letters (a, b, c, d) above the bars indicate significant differences (p < 0.05), where ab or bc represents the intermediate significance value between a and b or b and c, respectively.