| HPLC |
High Pressure Liquid Chromatography |
| CHO |
Chinese Hamster Ovary |
| MC |
Monte Carlo |
| FA |
Functional Analysis |
| Gln |
Glutamine |
| Lac |
Lactate |
|
biomass-specific growth rate |
|
biomass-specific product formation rate |
|
biomass-specific substrate uptake rate |
|
biomass-specific rate of component i |
|
concentration of component i |
| X |
biomass |
| S |
substrate |
| P |
product |
| D |
dilution rate |
|
substrate concentration in the feed |
|
feed rate |
|
t of sample k |
|
measured concentration at t |
|
true input |
|
reconstructed input by regression |
|
measured output |
|
predicted regression output |
|
weighting matrix of predictions |
|
weighting matrix of input variables |
| S |
weighted sum of squared error |
|
standard deviation of measured output or true input |
| N |
number of Monte Carlo iterations |
| f |
arbitrary function converting input to output
|
|
sampled input from Gaussian-distributed error |
|
calculation result of sampled input |
|
sampled input from output i |
|
standard deviation after calculation step i |
|
regression parameter for N Monte Carlo evaluations |
|
parameter covariance |
|
parameter standard deviation |
|
standard deviation of regression output |