α-SMA	alpha-smooth muscle actin
ABL	abetalipoproteinemia
ACVR2A	Activin A Receptor Type 2A
ADH	Alcohol Dehydrogenase
AF-B1	Aflatoxin B1
AGER	advanced glycosylation end product-specific receptor
ALDH	Aldehyde Dehydrogenase
ALIOS	American Lifestyle-Induced Obesity Syndrome
APOB	apolipoprotein B
Ath+HF	atherogenic and high-fat
BCAA	Branched-Chain Amino Acids
BMI	body mass index
CAR	chimeric antigen receptor
CD-HFD	choline-deficient high-fat diet
CDKI1A	cyclin dependent kinase inhibitor 1A
c-Jun	c-Jun N-terminal kinase
CRISPR/Cas9	clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9
CTNNB1	Catenin beta 1
CYP2E1	Cytochrome P450 2E1
DAMPs	damage-associated molecular patterns
DEN	diethylnitrosamine
DIAMOND	diet-induced animal model of non-alcoholic fatty liver disease
DNMT	DNA methyltransferases
EPIC	European Prospective Investigation into Cancer and Nutrition
ER	endoplasmic reticulum
EZH2	polycomb protein enhancer of zeste homolog 2
FFAs	free fatty acids
GWAS	genome-wide association study
HBV	hepatitis B infection
HCC	hepatocellular carcinoma
HDAC8	histone deacetylase 8
HFD	high-fat diet
HFHC	high fat high cholesterol
Ho-FHBL	hypobetalipoproteinemia
HPCs	hepatic progenitor cells
HR	hazard ratio
HSCs	hepatic stellate cells
HSD17B13	hydroxysteroid 17-β dehydrogenase 13
ILs	interleukins
IgA	Immunoglobulin A
IR	insulin resistance
KO	knock-out
LD	lipid droplet
LDL	low-density lipoprotein
Lyso-PI	lyso-phosphatidylinositol
LOX-1	lectin-like oxidized LDL receptor-1
LPIAT1	lyso-phosphatidylinositol (Lyso-PI) acyl-transferase1
LPS	lipopolysaccharides
MAT	methionine adenosyltransferase
MBOAT7	membrane bound o-acyltransferase domain-containing 7
MC4R	melanocortin 4 receptor-deficient mice
miRNA	microRNA
mtDNA	mitochondrial DNA
MT-ND6	mitochondrially encoded NADH dehydrogenase 6
MTTP	microsomal triglyceride transfer protein large subunit gene
NAFLD	nonalcoholic fatty liver disease
NASH	nonalcoholic steatohepatitis
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B-cells
NLRs	intracellular nucleotide-binding and oligomerization domain (NOD)-like receptors
OR	odd ratio
OS	overall survival
PAMPs	pathogen-associated molecular patterns
PD-1	death protein 1
PGC-1α	peroxisome proliferator-activated receptor γ coactivator-1α
PI	phosphatidylinositol
PNPLA3	patatin-like phospholipase domain-containing 3
PPARs	peroxisome proliferator activating receptors
PRSs	polygenic risk scores
PTEN	phosphatase and tensin homolog
PUFAs	polyunsaturated fatty acids
ROC	receiver operating characteristics
ROS	reactive oxygen species
RR	relative risk
SAM	S-adenyl methionine
SASP	senescence-associated secretory phenotype
SERCA	sarco/ER calcium ATPase
SIRTs	sirtuins
SNP	single nucleotide polymorphism
SR-A	scavenger receptor
SREBP1	Sterol Regulatory Element Binding Transcription Factor 1
STZ	streptozotocin
STAT3	Signal Transducer and Activator of Transcription 3
T2D	type 2 diabetes
TERT	telomerase reverse transcriptase
TG	triglyceride
TGF-β	transforming growth factor β
TLRs	toll like receptors
TM6SF2	transmembrane 6 superfamily member 2
TMC4	transmembrane channel like 4
TNF-α	tumor necrosis factor α
uPA	urokinase plasminogen activator
UPR	unfolded protein response
VLDL	very-low density lipoproteins
WD	Western diet
WNT	wingless