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. 2021 Oct 21;10(11):1283. doi: 10.3390/antibiotics10111283

Table 1.

Antibiotic profile of test species to a range of antibiotics from varying drug classes with EUCAST target zones given for species for which such information is available. Presence of β-lactamase genes in species is also listed, where ^ denotes broad-spectrum β-Lactamase producer, * denotes ESBL producer, and ** denotes ESBL and AmpC producer.

Drug Class AG CHL Macrolide Penicillin Penicillin-Like Cephalosporins Monobactam Carbapenems Quinolones Polymyxin TET Genes Identified
Antibiotic S CHL AZM ERY PEN AMP AMC CTX CRO CPD AZT DOR MEM IPM CIP LEV CT DOX
Conc. µg/Disk 10 30 15 15 10 10 20:10 5 30 10 30 10 10 10 5 5 10 50 30
A. baumanii * 13 9 16 9 0 R 8 19 16 17 15 11 29 A I 25 B S 30 D S 30 D S 32 H S 0 R 13 10 blaTEM
A. beijerinckii * 18 21 16 20 0 R 8 19 11 15 13 18 28 A I 23 B S 30 D S 16 D R 21 H I 0 R 14 14 blaTEM
A. lwoffii * 19 25 26 21 13 18 21 17 25 19 8 20 A R 24 B S 30 D S 24 D S 30 H S 14 14 25 blaTEM
P. aeruginosa * 0 R 0 R 0 R 0 R 0 R 0 R 0 R 0 R 0 R 0 R 0 R E 0 R A 0 R E 19 H R 0 R G 0 R A 14 19 10 blaTEM
P. fulva * 13 0 R 0 R 0 R 0 R 0 R 8 9 20 0 R 20 E I 21 A R 16 E R 30 H I 26 G I 20 A R 14 18 12 blaTEM
P. fluorescens * 16 16 14 12 0 R 0 R 15 16 19 13 15 E R 20 A R 17 E R 25 H I 25 G R 24 A S 14 16 19 -
E. coli ** 9 18 J S 0 R 0 R 0 R 0 R L 12 L R 16 J R 17 A R 15 D R 12 D R 21 D I 23 K S 20 M I 24 A I 24 M S 13 15 9 blaTEM, blaAmpC
K. pneumoniae * 8 0 R J 13 0 R 0 R 0 R L 0 R L 22 J S 21 A R 16 D R 19 D R 25 D S 26 K S 30 M S 10 A R 13 M R 12 16 0 R blaTEM
C. freundii * 0 R 17 J R 0 R 0 R 0 R 0 R L 20 L S 16 J R 19 A R 18 D R 18 D R 14 D R 17 K I 22 M I 24 A I 22 M I 11 15 17 blaCTX-M1
P. pulmonis * 0 R 13 14 10 0 R 0 R 16 0 R 20 20 0 R 25 27 30 19 19 17 20 15 blaTEM
P. mirabilis ^ 10 18 J 0 R 0 R 10 10 L R 17 L S 26 J S 26 A S 26 D S 30 D S 10 D R 18 K I 15 M R 32 A S 30 M S 0 R 0 R 0 R blaTEM
P. penneri ^ 10 0 R J 0 R 0 R 0 R 0 R L 8 L R 24 J S 25 A S 24 D S 33 D S 19 D R 20 K I 20 M I 20 A R 19 M I 0 R 0 R 0 R blaTEM
N. gonorrhoea 0 R 29 0 R 0 R 27 27 29 27 29 30 29 28 30 40 26 30 0 R 0 R 15 -

Abbreviations: AG = aminoglycoside, S = streptomycin, CHL = chloramphenicol, AZM = azithromycin, ERY = erythromycin, PEN = penicillin, AMP—ampicillin, AMC = amoxicillin-clavulanic acid, CTX = cefotaxime, CRO = ceftriaxone, CPD = cefpodoxime, AZT = aztreonam, DOR = doripenem, MEM = meropenem, IPM = imipenem, CIP = ciprofloxacin, LEV = levofloxacin, CT = colistin, TET = tetracycline, and DOX = doxycycline. ^ Broad-spectrum β-Lactamase producer, * ESBL producer, ** ESBL and AmpC producer. EUCAST target zones to indicate susceptibility represented by alphabetical lettering (A = 22 mm, B = 15 mm, D = 21 mm, E = 18 mm, G = 26 mm, H = 20 mm, J = 17 mm, K = 16 mm, L = 14 mm, and M = 19 mm) where S denotes “Susceptible”, I denotes “Susceptible, increased exposure, and R denotes “Resistance” to antibiotic drug.