. 2021 Oct 21;10(11):1283. doi: 10.3390/antibiotics10111283

Table 2.

MIC results for test species for selected antibiotics and test agent phendione based on EUCAST microdilution plate assay, where MICs for N. gonorrhoea were based on gradient test strips and agar dilution method.

Test Species	Antibiotic (µg/mL)														Test Agent (µg/mL)
Test Species	ERY	AZM	AMX	AMC	CAZ (3rd)	CRO (3rd)	FEP (4th)	AZT	DOR	MEM	CIP	CHL	DOX	CT	Phendione
A. baumanii	32	4	n.d. R	n.d. R	64	64	64	48	0.125 ^A S	0.19 ^B S	0.19 ^E I	128	12	4^A R	0.78
A. beijerinckii	8	2	32	1	12	32	12	n.d. R	0.094 ^A S	0.19 ^B S	0.19 ^E I	12	6	6 ^A R	1.56
A. lwoffii	16	1	n.d. R	n.d. R	4	6	1	n.d. R	0.064 ^A S	0.125 ^B S	0.038 ^E S	6	0.5	1.5 ^A S	0.39
P. aeruginosa	n.d. R	n.d. R	n.d. R	n.d. R	n.d. R ^B	n.d. R	n.d. R ^B	n.d. R ^H	4 ^A R	32 ^B R	n.d. R ^D	n.d. R	24	n.d. R^A	15
P. fulva	96	n.d. R	n.d. R	24	n.d. R ^B	32	24 ^B R	n.d. R ^H	0.5 ^A S	1 ^B S	0.25 ^D I	n.d. R	48	6 ^A R	6.25
P. fluorescens	64	n.d. R	n.d. R	24	n.d. R ^B	n.d. R	n.d. R ^B	n.d. R ^H	0.19 ^A S	0.125 ^B S	0.38 ^D I	n.d. R	6	12 ^A R	3.125
E. coli	128	32	16 ^B R	16 ^B R	1 ^G S	3 ^A R	1.75 ^G S	6 ^G R	0.023 ^A S	0.023 ^B S	0.038 ^D S	8 ^B S	12	4 ^A R	6.25
K. pneumoniae	n.d. R	n.d. R	n.d. R ^B	n.d. R ^B	6 ^G R	2.5 ^A R	3 ^G S	5 ^G R	0.016 ^A S	0.5 ^B S	n.d. R ^D	n.d. R ^B	n.d. R	4 ^A R	6.25
C. freundii	n.d. R	n.d. R	n.d. R ^B	12 ^B R	4 ^G S	n.d. R ^A	n.d. R ^G	n.d. R ^G	32 ^A R	4 ^B I	0.4 ^D I	12 ^B R	24	32 ^A R	0.39
P. penneri	n.d. R	n.d. R	n.d. R ^B	1.5 ^B S	0.064 ^G S	0.016 ^A S	0.064 ^G S	0.047 ^G S	0.032 ^A S	0.5 ^B S	0.075 ^D S	n.d. R ^B	n.d. R	n.d. R ^A	6.25
P. mirabilis	n.d. R	n.d. R	128 ^B R	1.5 ^B S	0.064 ^G S	0.016 ^A S	0.064 ^G S	0.016 ^G S	0.047 ^A S	1 ^B S	0.023 ^D S	24 ^B R	n.d. R	n.d. R ^A	6.25
P. pulmonis	n.d. R	n.d. R	n.d. R	1	n.d. R	n.d. R	n.d. R	n.d. R	0.006	0.023	2	n.d. R	64	8	0.39
N. gonorrhoea	n.d. R	n.d. R^D	0.016	0.016	0.16	0.094 ^J S	0.047	0.032	0.004	0.023	0.012 ^K S	0.5	4	n.d. R	0.39

Abbreviations: n.d. = non determined (concentrations up to 256 µg/mL tested), ERY = erythromycin, AZM = azithromycin, AMX = amoxicillin, AMC = amoxicillin-clavulanic acid, CAZ = ceftazidime, CRO = ceftriaxone, FEP = cefepime, AZT = aztreonam, DOR = doripenem, MEM = meropenem, IPM = imipenem, CIP = ciprofloxacin, CHL = chloramphenicol, DOX = doxycycline, and CT = colistin. EUCAST MIC cutoff points for susceptibility are represented by alphabetical lettering (^A = 2 µg/mL, ^B = 8 µg/mL, ^D = 0.5 µg/mL, ^E = 1 µg/mL, ^G =4 µg/mL, ^H = 16 µg/mL, ^J = 0.125 µg/mL, and ^K = 0.06 µg/mL) where S denotes “Susceptible”, I denotes “Susceptible, increased exposure, and R denotes “Resistance” to antibiotic drugs.