Figure 7.

Stability of β2m amyloid fibrils against GdnHCl, monitored by ThT fluorescence. Amyloid fibrils were grown, and their stability was tested in the presence of 250 μM SDS (A–E) and 300 μM LPA (F–J) at 37 °C. Amyloid fibrils were incubated at various concentrations of GdnHCl for 24 h, and the remaining ThT fluorescence was measured as described in Section 2.7.2. Data were normalized for the maximal ThT intensities. The sigmoidal curves are guides to the eye.