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. 2021 Oct 22;9(11):1519. doi: 10.3390/biomedicines9111519

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The concentration of S1P and prostaglandin (PG)-E2 with its metabolites (dhk PG-E2) in peritoneal fluid measured by mass spectrometry. The peritoneal S1P levels were compared between the patients during the non-menstrual period (N = 24) and the menstrual period (N = 9) (a), and between the non-endometriosis (N = 19) and endometriosis patients (N = 14) (b). The S1P levels in the non-menstrual (N = 14 vs. N = 10, (c) and the menstrual periods (N = 5 vs. N = 4, (d) of non-endometriosis and endometriosis patients were compared. The concentration of PG-E2 and its metabolites (dhk PG-E2) was compared between the non-endometriosis (N = 5) and endometriosis patients (N = 9) (e). Bars show the median value. *, p < 0.05; N.S., not significant.