Figure 5.
Effects of melittin on the activation of brain-derived neurotrophic factor signaling. The result suggested that melittin enhanced the performance of the BDNF/TrkB/CREB pathway under Aβ25–35 (7 μM) challenge. To conduct this experiment: Seven hours after Aβ25–35 (7 μM) challenge, cells were lysed, and western blot was performed. Data are presented as mean ± standard deviation values of triple determinations. # p < 0.01, vs. control * p < 0.05, ** p < 0.01, vs. Aβ25–35 only-treated group.