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. 2021 Nov 9;10(11):1159. doi: 10.3390/biology10111159

Table 3.

Changes of Pro-IL-1β and Cleaved-IL-1β protein levels in the supernatants of macrophages exposed to ATP in the presence of serum obtained before and after a moderate consumption of alcohol-free beer or traditional beer during a period of four weeks. Values were normalized by the total amount of protein (Ponceau) and given as the mean ± SEM. Percentage of released IL-1β values were expressed as the levels of mature IL-1β released respect to the total (pro-IL-1β + cleaved-IL-1β).

Alcohol-Free Beer p-Value Traditional Beer p-Value
Before After Before After
Pro-IL-1 β (N = 8) 1.06 ± 0.2 1.20 ± 0.5 0.435 0.94 ± 0.2 1.03 ± 0.3 0.370
Cleaved-IL-1 β (N = 8) 1.58 ± 1.9 2.13 ± 3.1 0.424 1.46 ± 1.5 1.23 ± 1.1 0.418
% Released IL-1 β (N = 8) 36.6 ± 10.9 35.4 ± 11.3 0.506 40.3 ± 11.0 37.6 ± 10.4 0.045