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Effects of Vit C on the expression of pro-inflammatory markers in MPTP-treated mice. Real-time PCR analysis of (A) IL-6, (B) TLR4, (C) TNF-α, (D) iNOS, and (E) CD40 mRNA expression levels in controls (CTR), mice treated with Vitamin C (VIT C), MPTP, MPTP, and Vitamin C (MPTP+ VIT C) in striatum (left) and SNpc (right). Results are presented as mRNA fold changes relative to GAPDH, used as resident control. Data are presented as mean ± SD (* p < 0.05 vs. CTR; # p< 0.05 vs. MPTP).
