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. 2021 Oct 28;9(11):1556. doi: 10.3390/biomedicines9111556

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Two deep marine derived drugs are currently on the market: (a) Prialt^® and (b) Yondelis^®. The figure shows species and sampling depth from which the compounds have been isolated, their molecular targets and disease areas. (a) Ziconotide (Prialt^®) was derived from the venom of a marine snail (Conus sp.) and is used for the treatment of severe pain. (b) Trabectedin, ET-743 (Yondelis^®), was derived from a marine tunicate Ecteinascidia turbinate and is used for the treatment of soft tissue sarcoma and ovarian cancer.