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Chemical structures of (a) Prialt® and (b) Yondelis® FDA approved in 2004 and 2015, respectively. Chemical structures of Ziconotide (Prialt®; PubChem Identifier: CID 16135415) and Trabectedin, ET-743 (Yondelis®; PubChem Identifier: CID 108150), are from the public database PubChem (https://pubchem.ncbi.nlm.nih.gov/compound/Ziconotide#section=2D-Structure [20] and https://pubchem.ncbi.nlm.nih.gov/compound/Trabectedin#section=2D-Structure [21], both accessed on 11 October 2021).
