Table 3.
Marine Organism | Activity/Experimental Model | Depth/Site | Concentrations | Ref. |
---|---|---|---|---|
Aegina citrea | Citotoxicity test against Leukemia L1210 cells | 200–1000 m Sagami Bay |
IC50 = 100 mg/mL | [70] |
Crossota rufobrunea | Hemolytic activity test of suspension of sheep red blood cells | 200–1000 m Sagami Bay |
ED50 = 100 mg/mL | [70] |
Atolla wyvillei | Crustacean letality test against shrimp Palaemon paucidens | 200–1000 m Sagami Bay |
LD50 = 2 mg/g | [70] |
Abbreviations: IC50 for the concentration (μg/mL) inducing 50% loss of cell viability; ED50 for effective dose for 50% hemolysis of a 0.8% suspension of sheep red blood cells; LD50 for lethal activity; HSV1 for herpes simplex 1.