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. 2021 Nov 11;10(11):1381. doi: 10.3390/antibiotics10111381

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of UA (Ursolic acid) (vertical lines) and OA (Oleanolic acid) (lattice) on calcein release (A,B) and relief of fluorescence self-quenching of R18s-labeled liposomes (C,D) in lipid vesicles (POPG:CL, 85:15 (A,C) or POPG:CL, 60:40 (B,D). The ordinate shows the percentage of calcein released (A,B) or the percentage of R18-fluorescence dequenching (C,D) compared to what was observed after addition of 2% Triton X-100 (positive control, considered as 100%). Data (SEM) are representative of three independent experiments in triplicate. Significant differences were observed when comparing the effect induced by UA and OA. POPG (1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol), CL (cardiolipin).