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. 2021 Nov 15;10(11):1186. doi: 10.3390/biology10111186

Table 10.

Univariable and multivariable logistic regression in association with requirement of invasive ventilation (n = 245).

Prognostic Markers Odds Ratio Lower CL Upper CL p-Value
Univariable Logistic Regression
Age (years) 1.053 1.021 1.09 0.002
HSP27 (ng/mL) 1.108 1.003 1.225 0.041
sST2 (ng/mL) 1.79 1.39 2.373 <0.001
TNFR1 (ng/mL) 1.065 0.951 1.182 0.24
cCK18 (1000 U/L) 0.806 0.112 3.45 0.799
20S proteasome (µg/mL) 1.039 1.004 1.079 0.031
Multivariable Logistic Regression
Age (years) 1.055 1.02 1.096 0.003
HSP27 (ng/mL) 1.028 0.915 1.155 0.635
sST2 (ng/mL) 1.709 1.306 2.31 <0.001
20S proteasome (µg/mL) 1.032 0.993 1.074 0.094

CL, confidence-limit; sST2, soluble suppression of tumorigenicity 2; HSP27, heat shock protein 27; cCK18, caspase cleaved cytokeratin 18; TNFR1, tumor necrosis factor receptor 1.