Table 1.
Demographic characteristics of the overall cohort (n = 65) at baseline.
| Healthy Elderly (n = 16) |
MCI Patients (n = 49) |
p | |
|---|---|---|---|
| Demographics | |||
| CDR, mean (SD) | 0 | 0.5 | |
| Gender, female, n (%) | 13 (81.3) | 33 (67.3) | 0.357 a |
| Age, year, mean (SD) | 68.9 (5.9) | 69.9 (8.4) | 0.314 b |
| Education, year, mean (SD) | 9.6 (2.7) | 6.7 (4.4) | 0.003 b |
| MMSE, mean (SD) | 28.7 (1.1) | 25.3 (3.8) | <0.001 b |
| ADAS-cog, mean (SD) | 3.5 (1.7) | 9.4 (7.1) | 0.001 b |
| GSH level, ng/mL, mean (SD) | 4.1 (2.7) | 4.1 (2.5) | 0.726 b |
a Chi-square test; b Mann–Whitney U test; MCI, mild cognitive impairment; CDR, clinical dementia rating; MMSE, Mini-Mental Status Examination; ADAS-cog, the Alzheimer’s disease assessment scale-cognitive subscale; GSH, glutathione.