Table 3.

Multiple linear regression analyses of independent factors (including baseline GSH level) associated with cognitive change, measured by ADAS-cog score change from baseline to endpoint at month 24, in MCI patients (stepwise).

MCI Patients (n = 49)
Variable	B (SE)	t	p
Gender, female vs. male	−2.683 (1.556)	−1.724	0.091
Education, year	−0.309 (0.166)	−1.867	0.068
Baseline GSH level, ng/mL	0.882 (0.280)	3.149	0.003
Adjusted R square = 0.227

The regression model was adjusted with age, gender, education, and baseline GSH level. Significant variables are shown as p < 0.05. Abbreviations: GSH, glutathione; ADAS-cog, the Alzheimer’s Disease Assessment Scale-Cognitive Subscale; MCI, mild cognitive impairment.