Table 2.
Mean t1–t3 | t1 | t1–t2 | t2 | t2–t3 | t3 | |
---|---|---|---|---|---|---|
Age [years] (M ± SD) | 47.16 (13.29) | |||||
Sex | 53.3% male 46.7% female |
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BMI [kg/m2] (M ± SD) | 28.63 (5.35) | 28.31 (5.30) | 28.95 (5.50) | 28.90 (5.34) | ||
Weight group | 25.3% normal 74.7% overweight |
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Time [days] (M ± SD) |
317.51 (176.27) | 384.15 (227.52) | ||||
Euthymic (HAMD < 14 + YMRS < 9) (YES) | 74.7% | 92.0% | 84.0% | |||
Illness episode None Mania Depression |
58.7% 12.0% 29.3% |
53.3% 16.0% 29.3% |
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Tryptophan [µmol/L] (M ± SD) | 58.44 (9.46) | 57.89 (9.99) | 59.39 (9.32) | |||
Kynurenine [µmol/L] (M ± SD) | 2.23 (0.67) | 2.15 (0.65) | 2.21 (0.65) | |||
Kynurenine/tryptophan [µmol/mmol] (M ± SD) | 38.34 (10.83) | 37.72 (11.90) | 37.73 (12.04) | |||
Neopterin a [nmol/L] (M ± SD) | 7.09 (3.33) | 7.16 (3.39) | 7.48 (4.31) |
Note: a n = 68; BD = bipolar disorder; BMI = body mass index; HAMD = Hamilton Depression Scale; YMRS = Young Mania Rating Scale.