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. 2021 Oct 27;10(11):1308. doi: 10.3390/antibiotics10111308

Table 1.

An overview on the different types of nanotechnology based diagnostic methods.

Test Uses Advantages Disadvantages
Fungal detection biosensors
  • For diagnosis of invasive aspergillosis [62]

  • Detection of mycotoxins

  • Detection of fungal pathogens in agriculture [63]

  • High specificity

  • Very less usage of reagents required for calibration

  • Fast response time [64]

  • Poor sensitivity for many of the clinically relevant targets [65]

Diagnostics based on nucleic acids
  • Detection of fungal infections

  • Diagnosis of cancer

  • Identification of genetic markers related to cancer

  • Able to detect genetic markers in case of infectious diseases

  • Identify organisms without long isolation processes

  • Expensive

  • Radioactivity needed

  • False positives can occur [64].

Point of Care tests
  • Detecting presence of fungal pathogens

  • Blood glucose monitoring

  • Temperature monitoring

  • Rapid strep tests

  • Efficiency

  • Speedy diagnosis

  • Expanded testing capabilities [64]

  • Experienced and trained staff is required

  • Lack of cost-effectiveness [65]

Detection of Galactomannans
  • Diagnosis of invasive aspergillosis in conditions like acute leukemia and hematopoietic stem cell transplantation

  • Early diagnosis

  • Used for follow-up of therapy

  • Can detect even small levels

  • False positive or negative results can occur