Table 3.
Descriptions of the analytical methods previously developed to analyze MDA in EBC with DNPH derivatization.
| Reference | Technique | EBC Volume (µL) |
LOD (pg/mL) | LOQ (pg/mL) | Intermediate Precision (%) | Recovery (%) | N a | EBC Levels (pg/mL) |
|---|---|---|---|---|---|---|---|---|
| This study | LC-ESI-MS/MS | 125 | 70 | 211 | 9 | 92 | 164 | 115 (<LOD-886) b |
| [29] | LC-ESI-MS | 100 | 42 | 126 | 12 | 92 | 205 | 491 (294–711) c |
| [28] | LC-APCI-MS/MS | 100 | 72 | 216 | 7 | n.a. | 12 | 806 (77–1685) b |
a: number of samples analyzed; b: median with the range in parentheses; c: median above LOD with interquartile range into parentheses.