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ROS/Superoxide assay: Release of ROS/superoxide was induced by the exposure of PC12 cells to 80 µM 6-OHDA for 24 h. Simultaneously, the PC12 cells were treated with or with CB86 or CB204 (25 µM each) for 24 h. Results are expressed by mean ± SD (n = 8 replicates in each group). ANOVA followed by Bonferroni’s post-hoc test was performed, F (5, 42) = 75.18, p < 0.001. *** p < 0.001 vs. control, and * p < 0.05 compared to 6-OHDA+CB204.
