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Apoptosis assay: Apoptosis was induced by the exposure of PC12 cells to 80 µM 6-OHDA for 24 h. The PC12 cells were treated simultaneously with CB86 or CB204 (25 µM each) for 24 h. Results are expressed by mean ± SD (n = 8 replicates in each group). ANOVA followed by Bonferroni’s post-hoc test was performed, F (5, 42) = 85.07, p < 0.001. *** compared to control and ### compared to 6-OHDA, p < 0.001 for all comparisons.
