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Confocal photomicrographs showing immunolabeling for CB2 receptors (CB2r) and α3 and α4 subunits of the cholinergic nicotinic receptor (α3-nAChR and α4-nAChR) in the ventral tegmental area (VTA) and the nucleus accumbens (NAcc) of wild-type (WT) mice. Double labeling (yellow cells in panels aC, bC, cC and dC) indicates that α3- and α4-nAChRs colocalize with CB2r immunoreactive cells. Image adapted from Navarrete et al. Neuropsychopharmacology (2013) 38(12), 2515–2524.
