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. 2021 Oct 28;11(11):1435. doi: 10.3390/brainsci11111435

Table 3.

Characteristics of the studies included in the systematic review.

Study Participants (N) Age
(years)
Design Evaluation Outcomes Measuring Instrument Results
Del Din et al. (2020) [37] 128 71.68 ± 6.4 CG = 62
EG = 66
T0 = Baseline
T1 = 6 wk
Number of falls FRA The FRA index decreased significantly in the CG and EG (p ≤ 0.035).
Pelosin et al. (2020) [38] 24 71.9 ± 4.1 CG = 14
EG = 10
T0 = Baseline
T1 = 6 w
kT2 = 12 wk
Number of falls Schedule The EG and CG showed a significant time training interaction (F 1.33 = 7.39, p = 0.012).
EG = TM + VR reduced the number of falls (p < 0.001) with respect to CG = TM.
Santos et al. (2019) [39] 45 64.3 ± 8.5 CG = 15
EG1 = 15
EG2 = 15
T0 = Baseline
T1 = 8 wk
Balance
Risk of falls
BBS
TUG
No statistically significant differences between GG, EG1 and EG2 with respect to BBS (p = 0.968) and TUG (p = 0.824).
Significant differences found in pre and post intervention analyses of all outcomes.
The effect size was larger for EG2 = NW + CE in all functional tests.
Feng et al. (2019) [40] 28 66.93 ± 4.64
67.47 ± 4.79
CG = 14
EG = 14
T0 = Baseline
T1 = 12 wk
Balance
Risk of falls
BBS
TUG
After Tx, BBS and TUG scores improved significantly in both groups (p < 0.005).
The EG = VR showed improved performance compared to the CG = CP on BBS, TUG and Unified Parkinson’s Disease Rating Scale (p < 0.005).
Gandolfi et al. (2017) [41] 76 69.84 ± 9.41
67.45 ± 7.18
CG = 38
EG = 38
T0 = Baseline
T1 = 7 wk
T2 = 11 wk
Balance
Balance confidence activities
Number of falls
BBS
ABC
Self-reported
There were significant differences between the groups, with the EG = home VR showing improvement in the BBS (p = 0.04).
No significant differences between the groups for ABC and number of falls.
Significant pre/post-test differences in EG = home VR with respect to the number of falls (p = 0.034).
Mirelman et al. (2016) [42] 130 73 ± 5
74 ± 5
CG = 64
EG = 66
T0 = Baseline
T1 = 6 wk
T2 = 30 wk
Number of falls Incidence The number of falls was lower in the EG = TM + VR than in the CG = TM in patients diagnosed with Parkinson’s (p = 0.001).
Negrini et al. (2016) [43] 27 67 ± 9
66 ± 8
CG = 11
EG = 16
T0 = Baseline
T1 = 5 wk
T2 = 9 wk
Balance
Risk of falls
BBS
TT
FRA
The post hoc analysis showed significant differences between groups in the pre-test, post-test and follow-up (p < 0.02) on BBS and FRA, but no significant difference between the pre-test and follow-up in the Tinetti test (p = 0.2) in the EG.
No significant differences between the intervention groups (p> 0.005).
The effect size was large in BBS (d = 0.9); moderate in TT (d = 0.4) and small in FRA (d < 0.2) after the intervention.
Yang et al. (2016) [44] 23 72.5 ± 8.4
75.4 ± 6.3
CG = 12
EG = 11
T0 = Baseline
T1 = 6 wk
T2 = 8 wk
Balance
Risk of falls
BBS
TUG
Both groups obtained better results in relation to BBS and TUG after the intervention and at 8 weeks of follow-up (p < 0.001).
No significant differences between the groups after the test and at 8 weeks of follow-up.
Lee et al. (2015) [45] 20 70.1 ± 3.3
68.4 ± 2.9
CG = 10
EG = 10
T0 = Baseline
T1 = 6 wk
Balance BBS After 6 wk of Tx, BBS improved significantly in the EG (46.0 ± 1.3 to 48.1 ± 3.0; p < 0.05), but showed no significant improvement in the CG (45.0 ± 1.3 to 45.4 ± 1.5; p > 0.05).
Liao et al. (2015) [46] 36 64.6 ± 8.6
65.1 ± 6.7
67.3 ± 7.1
CG = 12
EG1 = 12
EG2 = 12
T0 = Baseline
T1 = 6 wk
T2 = 10 wk
Dynamic balance
Sensory organization
Risk of fallsNumber of falls
MV/SOT
TUG
FES-I
EG1 and EG2 showed significant improvements in MV/SOT compared to the CG after treatment and at 1 month of follow-up (p < 0.001).
EG1 and EG2 showed significant improvements compared to the CG relative to follow-up (p < 0.001).
No significant differences between EG1 and EG2 relative to FES-I.
EG2 showed significant improvements in SOT, TUG, FES-I with respect to CG.

ABC = Activities-specific Balance Confidence Scale; BBS = Berg balance scale; CE = Conventional exercise; CG = Control group; CP = Conventional physiotherapy; EG = Experimental group; FES = Functional electrical stimulation; FES-I = Falls Efficacy Scale; FPE = Fall prevention education; FRA = fall rates relative to activity exposure index; HE = Healthy elderly patients; HT = Home training; IF = Idiopathic falls; MCI = Mild cognitive impairment; MV = Dynamic balance test; NDT = Neurodevelopmental treatment; NW = Nintendo Wii Fit; OA = Osteoarthritis; TM = Treadmill; TT = Tinetti Test; TUG = Timed Up and Go; Tx = Treatment; SIBT = Sensory Integration Balance Training; SOT = Sensory organization test; VR = virtual reality; WK = Weeks.