Figure A16.
X-ray diffraction (XRD) pattern of pure calcined AMS-6 mesoporous nanoparticles (blue) and the loaded AMS-6-Dox nanoparticles (red). The measurements of the pure calcined AMS-6 NPs reveal a highly ordered mesostructured with peaks of scatter in-between the pores of the nanoparticles. The typical XRD pattern of the pure sample display peaks at low angles of 2.4° and 4.8° with an intensity of 4.12 × 105 and 0.6 × 105 a.u., respectively. The loaded AMS-6-Dox sample curve shows small peaks at high angles of approximately 15° and 30° with intensities below 0.75 × 105 a.u., which are most likely the scattering patterns of crystallized Dox outside of the pores. The pores of the AMS-6-Dox still seem to be filled with DOX, since the pattern does not show any peaks at low angles, which would indicate scatterings between the pore walls of the nanoparticles.