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. 2021 Nov 8;11(11):1648. doi: 10.3390/biom11111648
FDA Food and Drug Administration,
MDSCs myeloid-derived suppressor cells,
JAK1 Janus kinase 1,
JAK2 Janus kinase 2,
B2M beta-2-microglobulin,
MHC-I major histocompatibility complex class 1,
STAT1 signal transducer and activator of transcription 1,
IFNGR1 interferon gamma receptor 1,
PTPN2 protein tyrosine phosphatase non-receptor type 2,
APLNR apelin receptor,
PBRM1 polybromo 1,
ARID2 AT-rich interaction domain 2,
BRD7 bromodomain containing 7,
USP22 ubiquitin-specific peptidase 22,
PTEN phosphatase and tensin homolog,
CDKN2A cyclin-dependent kinase inhibitor 2A,
SK1 sphingosine kinase-1,
HLA-I human leukocyte antigen class I,
APM antigen-processing machinery,
NGFR nerve growth factor receptor,
FMT fecal microbiome transplantation,
TMB tumor mutation burden,
ADAR1 adenosine deaminase acting on RNA 1,
ICAM1 intercellular adhesion molecule 1,
AUC area under curve,
CAFs cancer-associated fibroblasts,
BLIMP-1 B lymphocyte-induced maturation protein-1,
TIM3 T cell immunoglobulin domain and mucin domain 3,
BTLA B and T lymphocyte associated,
TAMs tumor-associated macrophages,
irAEs immune-related adverse events,
DCs dendritic cells,
STAT5 signal transducer and activator of transcription 5,
SHIP1 Src homology-2 domain-containing inositol 5-phosphatase 1,
SOCS1 suppressor of cytokine signaling 1,
BACH1 BTB domain and CNC homolog 1,
CEBPB CCAAT enhancer binding protein beta,
IL7R interleukin 7 receptor,
NF-κB nuclear factor kappa B,
AP-1 activator protein 1,
PTPRC protein tyrosine phosphatase receptor type C,
BCL6 B-cell lymphoma-6 protein,
IL13Rα1 interleukin 13 receptor alpha1,
AKT1 AKT serine/threonine kinase 1,
IRAK1 interleukin 1 receptor-associated kinase 1,
TRAF6 TNF receptor-associated factor 6,
STAT6 signal transducer and activator of transcription 6,
IRF4 interferon regulatory factor 4,
PPAR-γ peroxisome proliferator activated receptor gamma,
KLF13 Kruppel-like factor 13,
LIPA lysosomal acid lipase A,
EVs extracellular vesicles,
SMAD7 SMAD family member 7,
IGF2R insulin-like growth factor 2 receptor,
VEGFA vascular endothelial growth factor A,
FGF2 fibroblast growth factor 2,
NLK Nemo-like kinase,
ULBP2 UL16 binding protein 2,
TAP1 antigen processing 1,
HLA-A major histocompatibility complex class I, A,
BMDCs bone marrow-derived dendritic cells,
cDC1s conventional DC1s,
CXCL C-X-C motif ligand,
MMPs matrix metalloproteinases,
JNK c-Jun N-terminal kinase,
MITF microphthalmia-associated transcription factor,
TYR tyrosinase,
MLANA Melan-A/Mart-1,
CTL cytolytic T lymphocytes,
TRAF6 TNFR-associated factor 6,
IRAK1/2 Il-1R-associated kinase 1/2.