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. 2021 Nov 11;11(11):1487. doi: 10.3390/brainsci11111487

Figure 1.

Figure 1

Dihexa restored the decrease in AngIV in APP/PS1 mice. (A) The chemical structure of Dihexa. (B) AngIV levels in the brains of APP/PS1 and WT mice as detected by ELISA. Student’s t-test was used for two group comparisons. Columns represent mean ± SD (n = 6 per group) * p < 0.05 vs. age-matched vehicle-treated WT control mice. (C) Dihexa increases the AngIV levels in the brains of APP/PS1 mice. The data were analyzed by one-way ANOVA followed by Tukey’s post hoc test. Columns represent mean ± SD (n = 12 per group). * p < 0.05 vs. age-matched vehicle-treated WT control mice. # p < 0.05 vs. vehicle-treated APP/PS1 mice.