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. 2021 Nov 11;11(11):1487. doi: 10.3390/brainsci11111487

Figure 2.

Figure 2

Dihexa rescued the cognitive ability of APP/PS1 mice. (A) Dihexa improved spatial learning when locating the hidden platform. Data were analyzed by two-way repeated-measures ANOVA followed by Bonferroni’s multiple comparisons test. (B) Swimming speed was not significantly different among the groups during acquisition training. Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test. (C) Dihexa tended to increase the number of crossings in the target quadrant. Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test. Columns represent mean ± SD (n = 12 per group). * p < 0.05 vs. age-matched vehicle-treated WT control mice, # p < 0.05, vs. vehicle-treated APP/PS1 mice. & p < 0.05 vehicle-treated APP/PS1 mice.