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Direct visualization of 3D growth of Ovcar-3 cells under various treatments over time. In 3D culture, paclitaxel spheroids continue to grow to at the same rate of the control, while panobinostat is superior in effecting spheroid shrinkage. Spheroids exposed to cisplatin and cisplatin–paclitaxel grow at a rate similar to the control. Scale bar is 500 µm.
