Table 1.
Association of adverse pregnancy outcomes with risk of diabetes or risk factors for coronary heart disease and vascular disease. Great Obstetrical syndromes are strictly connected to adverse long-term health consequences. Women with a history of adverse pregnancy outcome appear to be at increased risk of metabolic and vascular diseases in later life.
Pregnancy Outcome | Incidence in Pregnancy % | Risk Factors Shown to be Perturbed after Pregnancy | Association or Risk Ratio (95% Cl) |
---|---|---|---|
Gestational diabetes | 1.9–5.0 | Lipids | Increased risk for type 2 diabetes, especially if recurrence of gestational diabetes in a subsequent Pregnancy. No data on Coronary heart disease |
Blood pressure | |||
Large vessel function | |||
Small vessel function | |||
Preeclampsia (PE) | 2–4 | Lipids | 1.9 (1.0–3.5) vs. pregnancy |
Clotting | induced hypertension alone | ||
Fasting insulin | 1.7 (1.3–2.2) vs. no-PE | ||
Large vessels function | 2.0 (1.5–2.5) vs. no-PE | ||
Low birth weight (<2500 g) | 5 | Not studied | 11.3 (2.5–36.1) vs. ≥3500 g |
7.1 (2.6–18.7) vs. ≥3500 g | |||
Preterm delivery (<37 weeks) | 5–6 | Not studied | 1.8 (1.3–2.5) vs. term deliv |
2.1.(1.2–3.5) vs. term deliv |
Modified and reproduced with permission from: Sattar and Greer 2002.