Table 6.

MolDock score and interacting residues of 1, 2, and 3 to human alpha-estrogen receptor (3ERT).

Ligands	MolDock Score (kcal/mol)	Hydrogen Bonding	Steric Interaction	Electrostatic Interaction
1	−144.638 ± 1.41	Thr347	Asp351 (3); Leu539 (2); Ala350; Met343; Leu354; Thr347; Leu525; Met522
2	−139.590 ± 0.37	Val534 (2)	Leu525 (4); Trp383 (4); Thr347; Leu346; Asp351; Leu539; Leu536; Met528
3	−162.832 ± 2.24	Thr347	Thr347 (2); Ala350; Asp351; Leu354; Leu525; Met522; Met528
4-hydroxtamoxifen	−165.042 ± 0,48	Arg394; Glu353	Ala350	Asp351