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. 2021 Nov 1;11(11):1453. doi: 10.3390/brainsci11111453

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Complexity measure of evoked activity. (a) The curves connect the mean PCI obtained by averaging across the PCI values of the two stimuli for each experiment. The squares are relative to the PCI values of the single stimuli. (b) The perturbational complexity index (PCI) increases significantly in carbachol by 22% (p = 0.023, two-way ANOVA with factor drug treatment). (c,d) The binary matrix of significant sources relative to exp1, in basal (c) and CCh (d) conditions. The CCh administration caused a decrease in source entropy (0.55 basal, 0.21 CCh). (e,f) In exp9, the binary matrices of significant sources have comparable source entropies across conditions (0.92 basal, 0.93 CCh). The dots in the panels (c–f) correspond to the significant spatial-temporal activations.