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. 2021 Oct 23;11(11):1573. doi: 10.3390/biom11111573

Figure 1.

Figure 1

Circulating levels of corticosterone are elevated while adiponectin levels are suppressed by acute cold stress. Acute cold stress increased the circulating levels of corticosterone (A), while suppressed the levels of T3 (B) and adiponectin (C) in serum. White dots, No cold group (mice housed at 22 °C, n = 4–8); gray dots, 10 h cold group (mice housed at 6 °C for 10 h, n = 5–7); black dots, 48 h cold group (mice housed at 6 °C for 48 h, n = 4–6). (D). Treatment of hydrocortisone suppressed expression and release of adiponectin in differentiated 3T3-L1 adipocytes in a dose-dependent manner despite no significant effect when treated with CL or T3 for 24 h. (E) Circulating levels of corticosterone did not significantly alter at 30 °C or after 6 days of cold exposure. Each black dot indicates the individual mouse. (F) Adiponectin expression showed little change between mice housed at 22 °C and 30 °C. White dots, mice housed at 22 °C, n = 6; gray dots, mice housed at 30 °C, n = 6. ADPN, adiponectin. The data in Figure 1A–C are presented as mean ± S.E.M. * p < 0.05, ** p < 0.01.