Figure 3.

Metabolic role of the SLC25A members involved in NMDs. Mitochondrial carriers are indicated with the coding gene name, and the main transported substrates, when known, are reported. α-KAdip, α-ketoadipate; α-KG, α-ketoglutarate; ASP, aspartate; β-OX, β-oxidation; CIT, citrate; CoA, coenzyme A; FAD, flavin adenine dinucleotide; FUM, fumarate; GLU, glutamate; ISO, isocitrate; MAL, malate; MIM, mitochondrial inner membrane; OAA, oxaloacetate; PAP, adenosine 3′,5′-diphosphate; Pi, inorganic phosphate; PYR, pyruvate; SUC, succinate; TCA, tricarboxylic acid; THF, tetrahydrofolate.