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. 2021 Nov 17;9(11):1703. doi: 10.3390/biomedicines9111703

Figure 2.

Figure 2

(A) Metabolic activity of U87 MG cells and (B) LDH activity in the dark (white columns), after PBM (red columns), hypericin-PDT (orange columns) and PBM-hypericin-PDT (orange columns with red patterns). Hypericin concentration was 500 nM (administered to cells for 3 h). Cell damage was also induced by 100 nM and 10 µM rotenone for 24 h. Significance level (against controls without hypericin treatment) was estimated using the one-way ANOVA-test: a (dark), b (PBM), c (PDT), d (PBM + PDT) < 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.