Table 1.

Shared genes and factors associated with ASD and AD.

Sr. No.	Genes Associated with ASD and AD	Reference
1	MECP2 (methyl-CpG binding protein 2)	[102,103].
2	ADNP (activity-dependent neuroprotective protein)	[20,104].
3	GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B)	[105,106,107].
4	SCN2A (sodium voltage-gated channel alpha subunit 2)	[108,109].
5	NLGN (neuroligin)	[110,111,112].
6	CNTNAP2 (contactin-associated protein 2)	[113,114,115,116].
7	TSHZ3 (teashirt zinc finger homeobox 3)	[117,118,119].
8	SHANK	[120,121,122,123,124].
9	PTEN (phosphatase and tensin homolog)	[125,126,127,128].
10	DYRK1A (dual-specificity tyrosine phosphorylation-regulated kinase 1A)	[129,130,131,132].
11	RELN (reelin)	[133,134,135].
12	FOXP1 (forkhead box protein P1)	[136,137,138,139].
13	SYNGAP1 (synaptic Ras GTPase-activating protein 1)	[140,141].
14	GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5)	[142,143].
15	UBE3A (ubiquitin-protein ligase E3A)	[144,145,146].
16	CYFIP1 (cytoplasmic FMR1-interacting protein 1)	[147,148].
17	NRXN (neurexin)	[149,150].
18	STX1A (syntaxin 1A)	[151,152,153].
19	DLG4 (discs large MAGUK scaffold protein 4)	[154,155,156].
20	AKAP9 (A-kinase anchoring protein 9)	[157,158].
21	CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3)	[159,160,161].
22	GSTT1(glutathione S-transferase theta-1), GSTM1(glutathione S-transferase Mu 1), GSTP1(glutathione S-transferase pi 1)	[162,163].
23	FMR1 (fragile X mental retardation 1)	[164,165,166].
24	APOE (apolipoprotein E)	[167,168,169,170].
25	APP (beta-amyloid precursor protein)	[171,172].
26	BDNF (brain-derived neurotrophic factor)	[173,174,175,176].
27	TNF (tumor necrosis factor)	[177,178].
28	SLC6A4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4)	[179,180].