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List of identified germline genes that have been implications in advanced prostate cancer from seminal work from Pritchard et al. [11].
| Gene | % Prevalence Pathological Gene Mutation in Metastatic PCa |
|---|---|
| BRCA2 | 5.53% |
| CHEK2 | 1.87% |
| ATM | 1.59% |
| BRCA1 | 0.87% |
| GEN1 | 0.46% |
| PALB2 | 0.43% |
| RAD51D | 0.43% |
| ATR | 0.29% |
| PMS2 | 0.29% |
| BRIP1 | 0.18% |
| FAM175A | 0.18% |
| MSH2 | 0.14% |
| MSH6 | 0.14% |
| RAD51C | 0.14% |
| MRE11A | 0.14% |
