Figure 2.

A 73-year-old man with high PSA (5.31 ng/mL): as dynamic range (DR) decreases from 70 to 30, a tumor (white arrow) becomes clear because of increasing tissue contrast. Subsequently, radiologists or urologists can detect and target it easily. The numbers of target and systematic cores were 4 and 4, respectively. Adnocarcinoma was confirmed with only target biopsy. The highest Gleason scores of tumor center and periphery were 8 (4 + 4) and 9 (4 + 5), respectively. Good lesion depiction could reduce the number of cores compared to 12-core systematic biopsy. However, as the DR decreases, gray-scale images becomes coarse because of decreasing tissue resolution. We recommend that the DR should be maintained from 40 to 50.