Table 5.
Dose constraints for organs at risk for moderate hypofractionation in 20 fractions (control arm). Rectum_adapt will be generated by delineation of the rectum in the co-registered CB-CTs, MV-CTs or MRI images of the first three fractions. Manual delineation of the Rectum_adapt should consider the mean rectal volume.
| Organ | Dose for 20 Fractions (Gy) | Max. Volume (%) Optimal |
Max. Volume (%) Mandatory |
|---|---|---|---|
| Rectum or Rectum Adapt | Dose for 20 Fractions (Gy) | Max Volume (%) | Max Volume (%) |
| 20 | 85 | ||
| 25 | 80 | ||
| 30 | 57 | ||
| 40 | 38 | 50 | |
| 50 | 22 | ||
| 57 | 5 | 10 | |
| 60 | 0.01 | 0.3 | |
| Bladder | Dose for 20 fractions (Gy) | Max volume (%) | Max volume (%) |
| 40 | 30 | 40 | |
| 50 | 15 | 25 | |
| 60 | 3 | 5 | |
| Femoral head left and right | Dose for 20 fractions (Gy) | Max volume (%) | |
| 41 | 50 | ||
| Penile bulb | Dose for 20 fractions (Gy) | Max volume (%) | Max volume (%) |
| 41 | 50 | ||
| 49 | 20 | ||
| Sigmoid | Dose for 20 fractions (Gy) | Max volume (%) | Max volume (cc) |
| 53 | 3 | ||
| Small bowel | Dose for 20 fractions (Gy) | Max volume (cc) | |
| 41 | 17 | ||
| 47 | Dmax | ||