Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 12;13(22):5661. doi: 10.3390/cancers13225661

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

PVT treatment induces autophagosome formation, lysosomal acidification, and fusion of autophagosome with lysosome. (A) Autophagy induction by PVT treatment was confirmed by confocal microscopy in AsPC1 cells. (B) Localization of acidic lysosomes was confirmed by LysoTracker assay in AsPC1 cells treated with 7.5 µM PVT. (C) Electron microscopic images of control and PVT treated AsPC1 cells showing effect of PVT on autophagosome formation and autophagosome—lysosome fusion. Statistically significant when compared with that of control.